Hematopoiesis Activity of Sambucus javanica on Chloramphenicol-induced Aplastic Anemia Mouse Model
نویسندگان
چکیده
منابع مشابه
Clonal Hematopoiesis in Aplastic Anemia
WENTY-FIVE YEARS AGO, William Dameshek, T the founder of this journal and one of the most creative minds in American hematology, raised a provocative question: what do aplastic anemia (AA), paroxysmal nocturnal hemoglobinuria (PNH), and acute leukemia have in common?’ His question was prompted by three observations: (1) the frequency of development of PNH in his own patients with AA, (2) the ov...
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Objective(s): The current work aimed to assess whether curcumin and baicalein can chelate iron in aplastic anemia (AA) complicated with iron overload, exploring the potential mechanisms.Materials and Methods: A mouse model of AA with iron overload complication was firstly established. Low and high-dose curcumin or baicalein treatment gro...
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Clonal hematopoiesis (CH) in aplastic anemia (AA) has been closely linked to the evolution of late clonal disorders, including paroxysmal nocturnal hemoglobinuria and myelodysplastic syndromes (MDS)/acute myeloid leukemia (AML), which are common complications after successful immunosuppressive therapy (IST). With the advent of high-throughput sequencing of recent years, the molecular aspect of ...
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Chloramphenicol is a widely used antibiotic. It is also well known to cause some potentially lethal complications such as aplastic anemia, acute leukemia and paroxysmal nocturnal haemoglobinuria Al though development of aplastic anemia is relatively more frequent, evidence in favour of acute leukemia caused by chloramphenicol is mostly circumstantial. Very rarely, aplastic anemia caused by chlo...
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T H E R E C O o N I T ! O N of ampicillin-resistant Hemophilus influenzae ~ has increased the use of chloramphenicol, particularly in management of invasive infections caused by this bacterium. Bone marrow toxicity, however, is a serious hazard. Based primarily on clinical data, two different bone marrow toxicities have been proposed. Reversible bone marrow suppression is frequent and dose rela...
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ژورنال
عنوان ژورنال: Natural Product Sciences
سال: 2019
ISSN: 1226-3907,2288-9027
DOI: 10.20307/nps.2019.25.1.59